Fast Food Restaurant – illustrative photo

Fast Food RestaurantNatick, MA

Five Guys – Natick, MA

Open now · closes 9:30 PM

Directions Call

Illustrative photo

Opening hours

Open now · closes 9:30 PM

Weekly opening hours of Five Guys
Monday	11:00 AM – 9:30 PM
Tuesday	11:00 AM – 9:30 PM
Wednesday	11:00 AM – 9:30 PM
Thursday	11:00 AM – 9:30 PM
Friday	11:00 AM – 9:30 PM
Saturday	11:00 AM – 9:30 PM
Sunday	11:00 AM – 9:30 PM

Local time in Natick: 12:10 PM (EDT). Holiday hours may differ – call (508) 650-5100 to confirm.

Location & directions

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221 North Main Street
Natick, MA 01760

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About Five Guys

Five Guys is a fast food restaurant you'll find at 221 North Main Street in Natick, Massachusetts. Our Natick guide covers 40 food and drink spots, and this is one of them.

Five Guys is open daily, 11:00 AM – 9:30 PM.

You can visit for takeout. On the menu: burgers.

Phone: (508) 650-5100.

Quick facts

Category: Fast Food Restaurant · Burger
Address: 221 North Main Street, Natick, MA 01760
Phone: (508) 650-5100
Hours: Open daily, 11:00 AM – 9:30 PM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for fast food restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout

Reviews

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Frequently asked questions

What are Five Guys's opening hours?

Open daily, 11:00 AM – 9:30 PM. Monday: 11:00 AM – 9:30 PM; Tuesday: 11:00 AM – 9:30 PM; Wednesday: 11:00 AM – 9:30 PM; Thursday: 11:00 AM – 9:30 PM; Friday: 11:00 AM – 9:30 PM; Saturday: 11:00 AM – 9:30 PM; Sunday: 11:00 AM – 9:30 PM.

Is Five Guys open on Sunday?

Yes, Five Guys is open on Sundays: 11:00 AM – 9:30 PM.

Where is Five Guys located?

Five Guys is located at 221 North Main Street, Natick, MA 01760.

What is the phone number of Five Guys?

You can call Five Guys at (508) 650-5100.

Does Five Guys offer delivery or takeout?

Delivery is not listed for Five Guys, and takeout is available. Listed service options: takeout.